Mesenchymal stem cells (MSCs) as source of progenitors in cell therapy have been increasingly noticed. However the markers that identify the homogeneity and or purity of MSCs are still subject of debate. Though MSCs are isolated from various tissue sources such as BM, placenta, UCB, cord stroma, PB and adipose tissue, markers like CD73, CD90, CD29 and CD105 are routinely used to identify MSC population. With the recent interest in the therapeutics, need for absolute homogeneous cells are necessary to reduce the GVHD and other induced immune reactions. We investigated the heterogeneity of MSC markers on other cells types and show that these markers are expressed on human dermal and foreskin fibroblast. Exactly we do not know the purpose of these early progenitor markers on these cells but their expression would suggest it as late progenitors one step behind the formation of functional clones. Thus we propose that cells expressing early progenitors would be excellent source of induced progenitors in future or otherwise start new search for bunch of MSC specific biomarkers.